Chemistry:4-HO-McPT

From HandWiki

4-HO-McPT, also known as 4-hydroxy-N-methyl-N-cyclopropyltryptamine, is a psychedelic tryptamine derivative. It has serotonergic effects,[1] and has reportedly been sold as a designer drug since around 2016, but was not definitively identified by forensic laboratories until 2018.[2][3]

Interactions

Pharmacology

4-HO-McPT produces the head-twitch response, a behavioral proxy of psychedelic effects, in rodents.[4] It has been found to act as a serotonin reuptake inhibitor.[4]

Chemistry

Analogues

Analogues of 4-HO-McPT include methylcyclopropyltryptamine (McPT), N-cyclopropyltryptamine (NcPT), 4-AcO-McPT, 5-MeO-McPT, 4-HO-McPeT, 4-HO-MiPT, 4-HO-MALT, 4-HO-MiPT, 4-HO-MPT, and 4-HO-EPT, among others.

Society and culture

Finland

4-HO-McPT is illegal in Finland.[5]

See also

References

  1. ↑ Chadeayne, Andrew R, "Compositions comprising a psilocybin derivative and a cannabinoid", US patent application 2019142851, published 2019-05-16, now abandoned.
  2. ↑ "PeakAL: Protons I Have Known and Loved, Too — Another Fifty Shades of Grey-Market Spectra.". Blotter 3 (1). March 2018. doi:10.16889/isomerdesign-5. 
  3. ↑ "Analytical Report: 4-HO-McPT.". Nacionalni Forenzični Laboratorij. Slovenia. September 2018. https://www.policija.si/apps/nfl_response_web/0_Analytical_Reports_final/4-HO-McPT-ID-1961-18_report.pdf. 
  4. ↑ 4.0 4.1 "Serotonin Transporter Blockade Reduces the Psychedelic-Like Effects of 4-Methoxy-N-methyl-N-isopropyltryptamine and Related Analogs". ACS Chem Neurosci. May 2026. doi:10.1021/acschemneuro.6c00083. PMID 42200433. 
  5. ↑ Valtioneuvoston asetus kuluttajamarkkinoilta kielletyistä psykoaktiivisista aineista



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