Chemistry:2-Methyl-5-hydroxytryptamine

2-Methyl-5-hydroxytryptamine
Identifiers
	IUPAC name 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol;
CAS Number	78263-90-8 ;
PubChem CID	1574;
IUPHAR/BPS	218;
ChemSpider	1518 ;
KEGG	C13665 ;
ChEBI	CHEBI:31085 ;
ChEMBL	ChEMBL266591 ;
Chemical and physical data
Formula	C11H14N2O
Molar mass	190.246 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES Oc1cc2c(cc1)[nH]c(c2CCN)C;
	InChI InChI=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3 ; Key:WYWNEDARFVJQSG-UHFFFAOYSA-N ;
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Short description: Chemical compound

2-Methyl-5-hydroxytryptamine (2-Methylserotonin, 2-Methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT₃ receptor.^[1]^[2]^[3]

References

↑ "Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines.". Archiv der Pharmazie 326 (11): 893–899. 1993. doi:10.1002/ardp.19933261110. PMID 8274071.
↑ "5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum.". Naunyn Schmiedebergs Arch Pharmacol 342 (1): 9–16. 1990. doi:10.1007/bf00178965. PMID 2402303.
↑ "Serotonin Receptor Subtypes and Ligands". American College of Neurophyscopharmacology. 2000-01-01. http://www.acnp.org/g4/GN401000039/Ch039.html.

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Identifiers


IUPAC name 3-(2-aminoethyl)-2-methyl-1H-indol-5-ol
CAS Number	78263-90-8^N
PubChem CID	1574
IUPHAR/BPS	218
ChemSpider	1518^Y
KEGG	C13665^Y
ChEBI	CHEBI:31085^Y
ChEMBL	ChEMBL266591^Y
Chemical and physical data
Formula	C₁₁H₁₄N₂O
Molar mass	190.246 g·mol⁻¹
3D model (JSmol)	Interactive image
SMILES Oc1cc2c(cc1)[nH]c(c2CCN)C
InChI InChI=1S/C11H14N2O/c1-7-9(4-5-12)10-6-8(14)2-3-11(10)13-7/h2-3,6,13-14H,4-5,12H2,1H3^Y Key:WYWNEDARFVJQSG-UHFFFAOYSA-N^Y
^NY (what is this?) (verify)