Chemistry:2-Methyl-5-hydroxytryptamine

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Short description: Chemical compound
2-Methyl-5-hydroxytryptamine
2-Methyl-5-hydroxytryptamine.svg
2-Methyl-5-hydroxytryptamine - 2.png
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
ChemSpider
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC11H14N2O
Molar mass190.246 g·mol−1
3D model (JSmol)
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2-Methyl-5-hydroxytryptamine (2-Methylserotonin, 2-Methyl-5-HT) is a tryptamine derivative closely related to the neurotransmitter serotonin which acts as a moderately selective full agonist at the 5-HT3 receptor.[1][2][3]

See also

References

  1. "Selectivity of sterically fixed tryptamine and 5-methoxytryptamine derivatives for serotonin receptor subtypes, II: Structure-activity relationships and in vitro pharmacology of N-alkyl- and N,N-dialkyl-3- indolylbicyclo-[2.2.1]-heptane-2-amines.". Archiv der Pharmazie 326 (11): 893–899. 1993. doi:10.1002/ardp.19933261110. PMID 8274071. 
  2. "5-Methoxytryptamine and 2-methyl-5-hydroxytryptamine-induced desensitization as a discriminative tool for the 5-HT3 and putative 5-HT4 receptors in guinea pig ileum.". Naunyn Schmiedebergs Arch Pharmacol 342 (1): 9–16. 1990. doi:10.1007/bf00178965. PMID 2402303. 
  3. "Serotonin Receptor Subtypes and Ligands". American College of Neurophyscopharmacology. 2000-01-01. http://www.acnp.org/g4/GN401000039/Ch039.html.