Chemistry:Fenharmane

From HandWiki

Fenharmane (INN), also known as 1-benzyl-1,2,3,4-tetrahydronorharmane, is a sedative and tranquilizer of the β-carboline family.[1][2] It has been said to have actions similar to those of reserpine, a monoamine-depleting agent.[3][4][5][6] The drug has been reported to induce symptoms of depression analogously to reserpine.[7][8] Fenharmane was developed in Czechoslovakia in the late 1950s.[3][2][9]

See also

References

  1. ↑ The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 144–145. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA144. 
  2. ↑ 2.0 2.1 "S31.03 The history of czech psychopharmacology and psychopharmacotherapy of affective and schizophrenic disorders". European Psychiatry 15 (S2): 277s. 2000. doi:10.1016/S0924-9338(00)94205-6. ISSN 0924-9338. https://www.cambridge.org/core/services/aop-cambridge-core/content/view/AC9F3DF4DA6BDC8F6675C31F7744115F/S0924933800048185a.pdf/div-class-title-s31-03-the-history-of-czech-psychopharmacology-and-psychopharmacotherapy-of-affective-and-schizophrenic-disorders-div.pdf. Retrieved 30 May 2025. 
  3. ↑ 3.0 3.1 "Reserpinový úćinek fenoharmanu" (in Czech). Ceskoslovenska Fysiologie 8 (3): 177–178. April 1959. PMID 13671512. 
  4. ↑ "[The reserpine-like action of 1-benzyl-1,2,3,4-tetrahydronorharmane (fenoharman)]" (in French). Journal de Physiologie 53: 488–489. 1961. PMID 13777950. 
  5. ↑ "[Nialamid and its combinations with reserpine-like substances (fenoharman, reserpine) in the therapy of endogenous depressions]" (in German). Deutsches Medizinisches Journal 13: 424–425. July 1962. PMID 14477998. 
  6. ↑ "[Comparative effects of Reserpine and Fenoharman on the absorption and liberation of serotonin in vivo and in vitro]" (in Czech). Activitas Nervosa Superior 4: 220–221. 1962. PMID 14495652. 
  7. ↑ "Akinesia: a syndrome common to parkinsonism, retarded depression, and negative symptoms of schizophrenia". Comprehensive Psychiatry 33 (4): 221–232. 1992. doi:10.1016/0010-440x(92)90045-r. PMID 1353715. 
  8. ↑ "Experimental Depression Caused by Apomorphine and Phenoharmane". Pharmacopsychiatry 5 (1): 13–19. 1972. doi:10.1055/s-0028-1094329. ISSN 0176-3679. http://www.thieme-connect.de/DOI/DOI?10.1055/s-0028-1094329. Retrieved 30 May 2025. 
  9. ↑ "[Use of Fenoharman, a new Czechoslovakian preparation, in psychiatry (preliminary communication)]" (in Czech). Casopis Lekaru Ceskych 99: 1422–1424. November 1960. PMID 13781443. 





Retrieved from "https://handwiki.org/wiki/index.php?title=Chemistry:Fenharmane&oldid=4036665"