Chemistry:SB-366791
From HandWiki
Short description: Chemical compound
 | |
| Identifiers | |
|---|---|
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| ChEBI | |
| ChEMBL | |
| Chemical and physical data | |
| Formula | C16H14ClNO2 |
| Molar mass | 287.74 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
SB-366791 is a drug which acts as a potent and selective blocker of the TRPV1 ion channel. It has analgesic effects in animal studies, and is used in research into pain and inflammation.[1][2][3]
See also
References
- ↑ "New compound fires up pain research". Drug Discovery Today 8 (23): 1053. December 2003. doi:10.1016/s1359-6446(03)02928-3. PMID 14693457.
- ↑ "TRPV1 modulates morphine self-administration via activation of the CaMKII-CREB pathway in the nucleus accumbens". Neurochemistry International 121: 1–7. December 2018. doi:10.1016/j.neuint.2018.10.009. PMID 30292787.
- ↑ "Hypersensitivity Induced by Intrathecal Bradykinin Administration Is Enhanced by N-oleoyldopamine (OLDA) and Prevented by TRPV1 Antagonist". International Journal of Molecular Sciences 22 (7): 3712. April 2021. doi:10.3390/ijms22073712. PMID 33918267.
 |  |
