Chemistry:Ulobetasol

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Short description: Chemical compound
Ulobetasol
Ulobetasol.svg
Clinical data
Trade namesUltravate
Other names(6S,8S,9S,10S,11S,13S,14S,16S,17R)-17-(2-Chloroacetyl)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one, halobetasol (USAN US)
AHFS/Drugs.comProfessional Drug Facts
MedlinePlusa601060
ATC code
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC22H27ClF2O4
Molar mass428.90 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Ulobetasol (INN) or halobetasol (USAN) is a corticosteroid used to treat psoriasis.[1][2] It is a class I corticosteroid under the US classification and a group III corticosteroid under international classification, the most potent group of such drugs.[3][4]

Ulobetasol propionate is usually supplied as a 0.05% topical cream.[1] Ulobetasol is the strongest topical steroid available.[citation needed] It is also sold with tazarotene with 0.01% halobetasol and 0.045% tazarotene as a lotion branded as Duobrii (Bausch Health).

It is available as a generic medication.[5]

References

  1. 1.0 1.1 "Ultravate product monograph". https://pdf.hres.ca/dpd_pm/00053569.PDF. 
  2. DrugBank DB00596 . Retrieved 2020-01-04.
  3. "Class I topical corticosteroid use by psoriasis patients in an academic practice". The Journal of Dermatological Treatment 15 (4): 235–8. July 2004. doi:10.1080/09546630410033745. PMID 15764038. 
  4. ATC code D07AC21 (WHO). Retrieved 2020-01-04.
  5. "Ulobetasol international". 10 August 2020. https://www.drugs.com/international/ulobetasol.html. 

External links