Chemistry:Domoprednate
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Short description: Chemical compound
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| Trade names | Stermonid |
| Other names | Ro 12-7024; 11β-Hydroxy-D-homopregna-1,4-diene-3,20-dione 17α-butyrate |
| Routes of administration | Topical |
| Drug class | Corticosteroid; Glucocorticoid |
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| Formula | C26H36O5 |
| Molar mass | 428.569 g·mol−1 |
| 3D model (JSmol) | |
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Domoprednate (brand name Stermonid; developmental code name Ro 12-7024) is a synthetic glucocorticoid corticosteroid which was developed in the late 1970s and 1980s.[1][2][3][4][5]
References
- ↑ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 465–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA465.
- ↑ "A randomized trial on the D-homosteroid domoprednate (Ro 12-7024) in the treatment of dermatoses". Dermatologica 168 (3): 127–30. 1984. doi:10.1159/000249683. PMID 6370748.
- ↑ "Domoprednate (Stermonid), a topical D-homocorticosteroid, skin atrophy and telangiectasia. A double-blind, randomized comparison with hydrocortisone butyrate, betamethasone valerate, clobetasole propionate and placebo". Dermatologica 170 (4): 189–94. 1985. doi:10.1159/000249529. PMID 3888708.
- ↑ "The treatment of psoriasis with 0.1% domoprednate (a D-homocorticosteroid) and 0.1% betamethasone valerate ointment. A double-blind, randomized trial". Dermatologica 170 (4): 195–8. 1985. doi:10.1159/000249530. PMID 3888709.
- ↑ "Domoprednate, a new nonhalogenated topical steroid: comparison to hydrocortisone butyrate". Dermatologica 175 (3): 145–7. 1987. doi:10.1159/000248813. PMID 3653463.
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