Chemistry:Aglepristone
From HandWiki
Short description: Chemical compound
 | |
| Clinical data | |
|---|---|
| Trade names | Alizin |
| Other names | RU-46534; RU-534; 11β-[4-(Dimethylamino)phenyl]-17β-hydroxy-17α-[(Z)-propenyl]estra-4,9-dien-3-one |
| Drug class | Antiprogestogen; Antiglucocorticoid |
| ATC code | |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| UNII | |
| KEGG | |
| ChEMBL | |
| Chemical and physical data | |
| Formula | C29H37NO2 |
| Molar mass | 431.620 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
Aglepristone (INN) (brand name Alizin; former developmental code names RU-46534, RU-534) is a synthetic, steroidal antiprogestogen related to mifepristone which is marketed by Virbac in several European countries for use in veterinary medicine.[1][2][3] It is specifically used as an abortifacient in pregnant animals.[1][3][4] Aglepristone, similarly to mifepristone, also possesses some antiglucocorticoid activity.[5][6]
See also
References
- ↑ 1.0 1.1 "Pregancy Loss in the Bitch and Queen". Kirk's Current Veterinary Therapy XV. Elsevier Health Sciences. 1 December 2013. pp. 3009–. ISBN 978-0-323-22762-9. https://books.google.com/books?id=KlJKAgAAQBAJ&pg=PT3009.
- ↑ "Endocrine manipulation of reproduction.". Applied Animal Endocrinology. CABI. 2010. pp. 207–. ISBN 978-1-84593-755-3. https://books.google.com/books?id=Q-rP6Fc9-N4C&pg=PA207.
- ↑ 3.0 3.1 "Aglepristone". Saunders Handbook of Veterinary Drugs: Small and Large Animal. Elsevier Health Sciences. 3 November 2010. pp. 120–. ISBN 978-1-4377-0192-0. https://books.google.com/books?id=PeJTVfaAiYAC&pg=PT120.
- ↑ "Hormonal variation in bitches after early or mid-pregnancy termination with aglepristone (RU534)". Journal of Reproduction and Fertility. Supplement. Advances in reproduction in dogs, cats and exotic carnivores: proceedings of the fourth International Symposium on Canine and Feline Reproduction, Oslo, Norway, 29 June-1 July 2000 57: 243–8. 2001. ISBN 978-0-906545-37-9. PMID 11787157.
- ↑ "Induction of parturition with aglepristone in the Majorera goat". Reproduction in Domestic Animals = Zuchthygiene 46 (5): 882–888. October 2011. doi:10.1111/j.1439-0531.2011.01759.x. PMID 21320179.
- ↑ "Hormonal changes in spontaneous and aglépristone-induced parturition in dogs". Theriogenology 69 (4): 399–407. March 2008. doi:10.1016/j.theriogenology.2007.10.008. PMID 18054071.
 |  |
