Chemistry:Fluperolone

Short description: Chemical compound

Fluperolone

Clinical data
Other names	9α-Fluoro-11β,17α,21-trihydroxy-21-methylpregna-1,4-diene-3,20-dione
Drug class	Corticosteroid; Glucocorticoid
Identifiers
IUPAC name (8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-17-[(2S)-2-hydroxypropanoyl]-10,13-dimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
CAS Number	3841-11-0
PubChem CID	56841872
ChemSpider	32700976
UNII	S33056JLS5
Chemical and physical data
Formula	C22H29FO5
Molar mass	392.467 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@@H](C(=O)[C@]1(CC[C@@H]2[C@@]1(C[C@@H]([C@]3([C@H]2CCC4=CC(=O)C=C[C@@]43C)F)O)C)O)O
InChI InChI=1S/C22H29FO5/c1-12(24)18(27)21(28)9-7-15-16-5-4-13-10-14(25)6-8-19(13,2)22(16,23)17(26)11-20(15,21)3/h6,8,10,12,15-17,24,26,28H,4-5,7,9,11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1 Key:SLVCCRYLKTYUQP-DVTGEIKXSA-N

Fluperolone is a synthetic glucocorticoid corticosteroid which was never marketed. An acetate ester of fluperolone, fluperolone acetate, in contrast, has been marketed.