Chemistry:Formocortal

Formocortal
Clinical data
Other names	3-(2-chloroethoxy)-6-formyl-9α-fluoropregna-3,5-diene-11β,16α,17,21-tetrol-20-one 21-acetate
ATC code	S01BA12 (WHO) ;
Identifiers
	IUPAC name 2-[(1S,2S,4R,8S,9S,11S,12R,13S)-16-(2-chloroethoxy)-12-fluoro-19-formyl-11-hydroxy-6,6,9,13-tetramethyl-5,7-dioxapentacyclo[10.8.0.02,9.04,8.013,18]icosa-16,18-dien-8-yl]-2-oxoethyl acetate;
CAS Number	2825-60-7 ;
PubChem CID	17794;
DrugBank	DB13664 ;
ChemSpider	254985 ;
UNII	8E21R0Z4M5;
KEGG	D04244;
Chemical and physical data
Formula	C29H38ClFO8
Molar mass	569.06 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CC(=C5[C@@]4(CCC(=C5)OCCCl)C)C=O)F)O)C)OC(O2)(C)C;
	InChI InChI=1S/C29H38ClFO8/c1-16(33)37-15-23(35)29-24(38-25(2,3)39-29)12-20-21-10-17(14-32)19-11-18(36-9-8-30)6-7-26(19,4)28(21,31)22(34)13-27(20,29)5/h11,14,20-22,24,34H,6-10,12-13,15H2,1-5H3/t20-,21-,22-,24+,26-,27-,28-,29+/m0/s1 ; Key:QNXUUBBKHBYRFW-QWAPGEGQSA-N ;
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Short description: Chemical compound

Formocortal (INN), also known as fluoroformylone, is a corticosteroid used in dermatology^[1] and ophthalmology.^[2]

It was introduced in around 1970^[1] and is not known to be marketed as of 2021^[update].

References

↑ ^1.0 ^1.1 "[On the topical use of a new steroid, formocortal, in the treatment of phlebodermitis and in cutaneous auto- and homo-grafts]". Minerva Cardioangiologica 19 (11): 620–624. November 1971. PMID 4942789.
↑ "Evaluation of spontaneous contamination of ocular medications". Chemotherapy 47 (4): 304–308. 2001. doi:10.1159/000048538. PMID 11399868.

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