Chemistry:16α-Methyl-11-oxoprednisolone

Short description: Chemical compound

16α-Methyl-11-oxoprednisolone

Clinical data
Other names	Dexamethasone impurity J; 17α,21-Dihydroxy-16α-methylpregna-1,4-diene-3,11,20-trione
Drug class	Corticosteroid; Glucocorticoid
Identifiers
IUPAC name (8S,9S,10R,13S,14S,16R,17R)-17-Hydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione
CAS Number	2036-77-3
PubChem CID	68141632
ChemSpider	48063904
UNII	NJ0LL8HN9X
Chemical and physical data
Formula	C22H28O5
Molar mass	372.461 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@H]3C(=O)C[C@@]2([C@]1(C(=O)CO)O)C)C
InChI InChI=1S/C22H28O5/c1-12-8-16-15-5-4-13-9-14(24)6-7-20(13,2)19(15)17(25)10-21(16,3)22(12,27)18(26)11-23/h6-7,9,12,15-16,19,23,27H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,19-,20+,21+,22+/m1/s1 Key:PIDANAQULIKBQS-VUOZLLHNSA-N

16α-Methyl-11-oxoprednisolone, also known as dexamethasone impurity J, is a synthetic glucocorticoid corticosteroid which was reported in 1979 and was never marketed.