Chemistry:Diflorasone diacetate

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Short description: Chemical compound and topical steroid
Diflorasone diacetate
Diflorasone diacetate.png
Clinical data
Trade namesPsorcon
AHFS/Drugs.comMonograph
MedlinePlusa602019
License data
Pregnancy
category
  • US: C (Risk not ruled out)
Routes of
administration
Topical
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
IUPHAR/BPS
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC26H32F2O7
Molar mass494.532 g·mol−1
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Diflorasone diacetate is a topical steroid that comes in the form of a cream. It is manufactured by E. Fougera & Co. and is used as an anti-inflammatory and anti-itching agent, like other topical corticosteroids. It is prescribed for psoriasis[1] and atopic dermatitis, among other conditions. With respect to potency, it is regarded as a Class I corticosteroid [of classes I – VII] in the United States.[2]

No long-term animal studies have been done to determine whether diflorasone diacetate could have carcinogenic properties.[citation needed]

Little data is available regarding whether diflorasone diacetate would be present in great enough quantities to cause harm to an infant.[3]

References

  1. "Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis". Dermatology 186 (2): 129–32. 1993. doi:10.1159/000247323. PMID 8428041. 
  2. "Topical Steroids Potency Chart". psoriasis.org. https://www.psoriasis.org/sublearn03_mild_potency/. 
  3. "Diflorasone topical". Drugs.com. https://www.drugs.com/mtm/diflorasone-topical.html. 

External links