Chemistry:Tixocortol pivalate
From HandWiki
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| Names | |
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| IUPAC name
S-(11β,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl) 2,2-dimethylpropanethioate
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| Systematic IUPAC name
S-{2-[(1R,3aS,3bS,9aR,9bS,10S,11aS)-1,10-Dihydroxy-9a,11a-dimethyl-7-oxo-2,3,3a,3b,4,5,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthren-1-yl]-2-oxoethyl} 2,2-dimethylpropanethioate | |
| Identifiers | |
3D model (JSmol)
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PubChem CID
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| UNII | |
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| Properties | |
| C26H38O5S | |
| Molar mass | 462.64 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
 verify (what is   ?)
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| Infobox references | |
Tracking categories (test):
Tixocortol pivalate is a corticosteroid. It has anti-inflammatory properties similar to hydrocortisone.[1] It is marketed under the brand name Pivalone.[2]
It is sometimes used in patch testing in atopic dermatitis.[3]
See also
References
- ↑ P Larochelle MD, PhD; P Du Souich MD, PhD; E Bolte MD; J Lelorier MD, PhD; R Goyer PhD (1983). "Tixocortol pivalate, a corticosteroid with no systemic glucocorticoid effect after oral, intrarectal, and intranasal application". Clinical Pharmacology and Therapeutics 33 (3): 343–350. doi:10.1038/clpt.1983.43. PMID 6402333. http://www.nature.com/clpt/journal/v33/n3/abs/clpt198343a.html. Retrieved 2011-03-29.
- ↑ "Tixocortol Pivalate". Drugs.com. https://www.drugs.com/international/tixocortol-pivalate.html.
- ↑ "Patch testing in atopic dermatitis". Dermatitis 21 (5): 251–4. October 2010. doi:10.2310/6620.2010.10036. PMID 20920410. http://www.bcdecker.com/pubMedLinkOut.aspx?pub=AJCDO&vol=21&iss=5&page=251.
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