Biology:KIF6

Short description: Protein-coding gene in the species Homo sapiens

Generic protein structure example

Kinesin family member 6 is a protein that in humans is encoded by the KIF6 gene. This gene encodes a member of the kinesin family of proteins. Members of this family are part of a multisubunit complex that functions as a microtubule motor in intracellular organelle transport.

Further reading

• "[Association of a polymorphic marker Trp719Arg of KIF6 gene with effects of atorvastatin and simvastatin in patients with early ischemic heart disease]". Kardiologiia 51 (9): 4–12. 2011. PMID 21943003. 
• "Investigation of KIF6 Trp719Arg in a case-control study of myocardial infarction: a Costa Rican population". PLOS ONE 5 (9): e13081. September 2010. doi:10.1371/journal.pone.0013081. PMID 20927332. Bibcode: 2010PLoSO...513081B. 
• "Meta-analyses of KIF6 Trp719Arg in coronary heart disease and statin therapeutic effect". PLOS ONE 7 (12): e50126. 2012. doi:10.1371/journal.pone.0050126. PMID 23236363. Bibcode: 2012PLoSO...750126P. 
• "KIF6, LPA, TAS2R50, and VAMP8 genetic variation, low density lipoprotein cholesterol lowering response to pravastatin, and heart disease risk reduction in the elderly". Atherosclerosis 220 (2): 456–62. February 2012. doi:10.1016/j.atherosclerosis.2011.11.037. PMID 22192511. 
• "KLF6 loss of function in human prostate cancer progression is implicated in resistance to androgen deprivation". The American Journal of Pathology 181 (3): 1007–16. September 2012. doi:10.1016/j.ajpath.2012.06.008. PMID 22819534. 
• "The polymorphism Trp719Arg in the kinesin-like protein 6 is associated with the presence of late outgrowth endothelial progenitor cells in acute myocardial infarction". Atherosclerosis 210 (1): 48–50. May 2010. doi:10.1016/j.atherosclerosis.2009.11.041. PMID 20044086. 
• "Pharmacogenetic analysis of lipid responses to rosuvastatin in Chinese patients". Pharmacogenetics and Genomics 20 (10): 634–7. October 2010. doi:10.1097/FPC.0b013e32833de489. PMID 20679960. 
• "[Motor protein Kinesin-6 and ischemic heart disease]". Kardiologiia 50 (6): 54–62. 2010. PMID 20659029. 
• "Investigation of KIF6 Trp719Arg in a case-control study of coronary artery disease in Western Indians". Genetic Testing and Molecular Biomarkers 15 (12): 883–6. December 2011. doi:10.1089/gtmb.2011.0079. PMID 21810021.