Chemistry:Nepinalone

Short description: Chemical compound

Nepinalone

Clinical data
ATC code	R05DB26 (WHO)
Identifiers
IUPAC name 1-methyl-1-(2-piperidin-1-ylethyl)-3,4-dihydronaphthalen-2(1H)-one
CAS Number	22443-11-4
PubChem CID	3047788
ChemSpider	2310106 Y
UNII	L9806LPR7G
KEGG	D07396 Y
Chemical and physical data
Formula	C18H25NO
Molar mass	271.404 g·mol−1
3D model (JSmol)	Interactive image
SMILES O=C2C(c1ccccc1CC2)(CCN3CCCCC3)C
InChI InChI=1S/C18H25NO/c1-18(11-14-19-12-5-2-6-13-19)16-8-4-3-7-15(16)9-10-17(18)20/h3-4,7-8H,2,5-6,9-14H2,1H3 Y Key:RVXGRCNWGOHSDE-UHFFFAOYSA-N Y
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Nepinalone is a cough suppressant. Its brand names include Placatus, Tussolvina, and Nepitus.

The effect is evident after 20–30 minutes after administration and persists for at least 4 hours. It acts primarily at the level of the CNS, but also shows a slight activity in inhibiting the bronchospasm. In such use, it is less effective than codeine and more effective than dextromethorphan in inhibiting the tussive stimulus. [1]