Chemistry:Nivacortol

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Short description: Chemical compound
Nivacortol
Nivacortol.svg
Clinical data
Other namesNivazol; Nivazole; WIN-27914; Novozola; NEBO-174; 2'-(4-Fluorophenyl)-2'-H-pregna-2,4-dien-20-yno(3,2-c)pyrazol-17-ol
Drug classCorticosteroid; Glucocorticoid
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
Chemical and physical data
FormulaC28H31FN2O
Molar mass430.567 g·mol−1
3D model (JSmol)

Nivacortol (developmental code names WIN-27914 and NEBO-174; also known as nivazol and nivazole) is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2][3][4]

References

  1. The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 881–882. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA881. 
  2. "Nivazole". AdisInsight. Springer Nature Switzerland AG. http://adisinsight.springer.com/drugs/800019031. 
  3. "Five-Membered Heterocycles: 1,2-Azoles, Part 1. Pyrazoles". Modern Heterocyclic Chemistry. 1. John Wiley & Sons. 2011. pp. 649–. ISBN 978-3-527-33201-4. https://books.google.com/books?id=hMg_C2JvzqwC&pg=PA649. 
  4. "The determination of nivacortol in plasma using HPLC". Biomedical Chromatography 1 (4): 151–154. August 1986. doi:10.1002/bmc.1130010404. PMID 3506827.