Chemistry:Betamethasone valerate

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Short description: Chemical compound
Betamethasone valerate
Betamethasone valerate.svg
Clinical data
Trade namesBetnovate, Celestoderm, Ecoval 70, Hormezon
Other namesBetamethasone 17-valerate
AHFS/Drugs.comMonograph
Drug classCorticosteroid; glucocorticoid
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEBI
ChEMBL
Chemical and physical data
FormulaC27H37FO6
Molar mass476.585 g·mol−1
3D model (JSmol)

Betamethasone valerate is a synthetic glucocorticoid ester. It is the 17-valerate ester of betamethasone.[1][2] Betamethasone valerate is often used to treat mild eczema with good efficacy and lower incidence of steroid induced adverse effects due to its lower potency compared to other glucocorticoids.[3] Betamethasone-17-valerate is available in cream, ointment, lotion, and foam preparations for topical use.[3][4][5]

See also

  • Fusidic acid/betamethasone valerate

References

  1. "Role of betamethasone valerate 2.250 mg medicated plaster in the treatment of psoriasis and other dermatological pathologies: a review". Drugs in Context 7: 212539. 2018. doi:10.7573/dic.212539. PMID 30151017. 
  2. "Betamethasole valerate". PubChem. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/Betamethasone-valerate. 
  3. 3.0 3.1 "Tips and Tricks for Controlling Eczema". Immunology and Allergy Clinics of North America 39 (4): 521–533. November 2019. doi:10.1016/j.iac.2019.07.006. PMID 31563186. 
  4. "A Review of Topical Corticosteroid Foams". Journal of Drugs in Dermatology 18 (8): 756–770. August 2019. PMID 31424707. https://pubmed.ncbi.nlm.nih.gov/31424707/. 
  5. "Scalp psoriasis: topical calcipotriol 50 micrograms/g/ml solution vs. betamethasone valerate 1% lotion". International Journal of Clinical Pharmacology Research 20 (3–4): 65–68. 2000. PMID 11314240. https://pubmed.ncbi.nlm.nih.gov/11314240.