Chemistry:Cloticasone

Short description: Chemical compound

Cloticasone

Clinical data
Other names	6α,9α-Difluoro-11β,17α-dihydroxy-16α-methyl-21-thia-21-chloromethylpregna-1,4-dien-3,20-dione; S-(Chloromethyl) 6α,9α-difluoro-11beta,17α-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioate
Drug class	Corticosteroid; Glucocorticoid
Identifiers
IUPAC name S-(Chloromethyl) (6S,8S,9R,10S,11S,13S,14S',16R,17R)-6,9-difluoro-11,17-dihydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17-carbothioate
CAS Number	87556-66-9
PubChem CID	44481798
ChemSpider	21476738
UNII	6CN32ZUQ4X
Chemical and physical data
Formula	C22H27ClF2O4S
Molar mass	460.96 g·mol−1
3D model (JSmol)	Interactive image
SMILES C[C@@H]1C[C@H]2[C@@H]3C[C@@H](C4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)SCCl)O)C)O)F)C)F
InChI InChI=1S/C22H27ClF2O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14+,16+,17+,19+,20+,21+,22+/m1/s1 Key:ANLWAEZHUOEOTI-GQKYHHCASA-N

Cloticasone is a synthetic glucocorticoid corticosteroid which was never marketed.