Chemistry:Clocortolone pivalate
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Short description: Chemical compound
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| Trade names | Cilder, Cloderm, Purantix |
| Other names | Clocortolone trimethylacetate; CL-68; SH-863; 9α-Chloro-6α-fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-pivalate |
| Drug class | Corticosteroid; Glucocorticoid |
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| Formula | C27H36ClFO5 |
| Molar mass | 495.03 g·mol−1 |
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Clocortolone pivalate (brand names Cilder, Cloderm, Purantix), also known as clocortolone trimethylacetate, is a synthetic glucocorticoid corticosteroid and corticosteroid ester which is marketed in the United States and Austria.[1][2][3] It is the C21 pivalate (trimethylacetate) ester of clocortolone,[1][2] and acts as a prodrug of clocortolone in the body.[4][5]
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. 14 November 2014. pp. 293–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA293.
- ↑ 2.0 2.1 Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 253–. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA253.
- ↑ Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. 6 December 2012. pp. 79–. ISBN 978-94-011-4439-1. https://books.google.com/books?id=tsjrCAAAQBAJ&pg=PA79.
- ↑ Bundgaard H, Nielsen NM, "Prodrug derivatives of carboxylic acid drugs", US patent 5073641, issued 17 December 1991
- ↑ Prodrugs: Challenges and Rewards. Springer Science & Business Media. 12 March 2007. pp. 220–. ISBN 978-0-387-49782-2. https://books.google.com/books?id=qkjHxX5TgHEC&pg=PA220.
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