Chemistry:Benzotript
From HandWiki
Benzotript (INN), also known as N-(p-chlorobenzoyl)-L-tryptophan, is a muscle relaxant that inhibits gastric secretion and was never marketed.[1][2] It is a tryptamine derivative and the N-(4-chlorobenzoyl) analogue of the amino acid tryptophan.[1] Similarly to proglumide (N2-benzoyl-N,N-dipropyl-α-glutamine), the drug acts as a competitive and non-selective cholecystokinin receptor antagonist.[2][3] Other more potent tryptophan derivatives have also been developed as cholecystokinin (CCK) antagonists.[2]
References
- ↑ 1.0 1.1 The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer US. 2014. p. 1262. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA1262. Retrieved 8 October 2024.
- ↑ 2.0 2.1 2.2 "Cholecystokinin antagonists: pharmacological and therapeutic potential". Med Res Rev 23 (5): 559–605. September 2003. doi:10.1002/med.10042. PMID 12789687.
- ↑ "Cholecystokinin antagonists". Horm Metab Res 18 (1): 2–9. January 1986. doi:10.1055/s-2007-1012212. PMID 2419234.
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