Chemistry:Methylprednisolone aceponate
From HandWiki
Short description: Chemical compound
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| Trade names | Advantan, Avancort |
| Other names | Methylprednisolone 17α-propionate 21-acetate; ZK-91588 |
| AHFS/Drugs.com | Consumer Drug Information |
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| Chemical and physical data | |
| Formula | C27H36O7 |
| Molar mass | 472.578 g·mol−1 |
| 3D model (JSmol) | |
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Methylprednisolone aceponate, or methylprednisolone acetate propionate, sold under the brand names Advantan and Avancort, is a glucocorticoid and a corticosteroid ester—specifically the C17α propionate and C21 acetate diester of methylprednisolone.[1][2][3]
In Russia and some other countries the drug is available in 4 dosage forms differing in consistency and water content: emulsion (or lotion), cream, ointment and fatty ointment.[4]
See also
References
- ↑ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 811–. ISBN 978-1-4757-2085-3. https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA811.
- ↑ Index Nominum 2000: International Drug Directory. Taylor & Francis. 2000. pp. 675–. ISBN 978-3-88763-075-1. https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA675.
- ↑ "Efficacy and safety of methylprednisolone aceponate ointment 0.1% compared to tacrolimus 0.03% in children and adolescents with an acute flare of severe atopic dermatitis". Allergy 62 (2): 184–9. February 2007. doi:10.1111/j.1398-9995.2006.01269.x. PMID 17298428.
- ↑ "Advantan (methylprednisolone aceponate) Full Prescribing Information Lists" (in Russian). https://grls.rosminzdrav.ru/GRLS.aspx?RegNumber=&MnnR=&lf=&TradeNmR=адвантан&OwnerName=&MnfOrg=&MnfOrgCountry=&isfs=0®type=1%2c6&pageSize=10&order=Registered&orderType=desc&pageNum=1.
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