Chemistry:SN-2
From HandWiki
Short description: Chemical compound
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| Formula | C17H21NO |
| Molar mass | 255.361 g·mol−1 |
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SN-2 is a chemical compound which acts as an "agonist" (i.e. channel opener) for the TRPML3 calcium channel, with high selectivity for TRPML3 and no significant activity at the related TRPML1 and TRPML2 channels.[1] It has demonstrated antiviral activity in an in vitro model.[2]
See also
References
- ↑ "Small molecule activators of TRPML3". Chemistry & Biology 17 (2): 135–48. February 2010. doi:10.1016/j.chembiol.2009.12.016. PMID 20189104.
- ↑ "ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity". Antiviral Research 182: 104922. October 2020. doi:10.1016/j.antiviral.2020.104922. PMID 32858116.
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