Biology:Methylprednisolone succinate

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Short description: Chemical compound
Methylprednisolone succinate
Methylprednisolone sodium succinate.svg
Clinical data
Trade namesSolu-Medrol, Solu-Medrone, Urbason, others
Other namesMethylprednisolone hemisuccinate; 6α-Methylprednisolone 21-hemisuccinate
AHFS/Drugs.comMonograph
License data
Routes of
administration
Intravenous injection
Drug classCorticosteroid; Glucocorticoid
ATC code
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEBI
ChEMBL
Chemical and physical data
FormulaC26H34O8
Molar mass474.550 g·mol−1
3D model (JSmol)

Methylprednisolone succinate, sold under the brand name Solu-Medrol among others, is a synthetic glucocorticoid corticosteroid and a corticosteroid ester—specifically the C21 succinate ester of methylprednisolone—which is used by intravenous administration.[2][3] Methylprednisolone succinate is provided as two different salts when used as a pharmaceutical drug: a sodium salt (methylprednisolone sodium succinate; brand name Solu-Medrol, others) and a hydrogen salt (methylprednisolone hemisuccinate or methylprednisolone hydrogen succinate; brand name Urbason).[2][3]

Methylprednisolone succinate was approved for medical use in the United States in 1959.[1]

References