Chemistry:Losoxantrone
From HandWiki
Short description: Chemical compound
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| Formula | C22H27N5O4 |
| Molar mass | 425.489 g·mol−1 |
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Losoxantrone (biantrazole) is an anthroquinone anthrapyrazole antineoplastic agent and analog of mitoxantrone.[1][2] It is also sometimes known as DuP 941.[3]
See also
- Mitoxantrone
- Piroxantrone
References
- ↑ "Anthrapyrazole anticancer agents. Synthesis and structure-activity relationships against murine leukemias". Journal of Medicinal Chemistry 30 (1): 121–31. January 1987. doi:10.1021/jm00384a021. PMID 3806589.
- ↑ "Anticancer anthrapyrazoles. Improved syntheses of clinical agents CI-937, CI-941, and piroxantrone hydrochloride". Journal of Heterocyclic Chemistry 26: 85–96. 1989. doi:10.1002/jhet.5570260117.
- ↑ "Topoisomerase II inhibition and cytotoxicity of the anthrapyrazoles DuP 937 and DuP 941 (Losoxantrone) in the National Cancer Institute preclinical antitumor drug discovery screen". Journal of the National Cancer Institute 86 (16): 1239–44. August 1994. doi:10.1093/jnci/86.16.1239. PMID 8040892. https://zenodo.org/record/1234355.
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