Chemistry:Trofosfamide

Short description: Chemical compound

Trofosfamide

Clinical data
Trade names	Ixoten
AHFS/Drugs.com	International Drug Names
Routes of administration	By mouth (film-coated tablets)
ATC code	L01AA07 (WHO)
Legal status
Legal status	DE: § 48 AMG/§ 1 MPAV (Prescription only)
Identifiers
IUPAC name N,N,3-tris(2-chloroethyl)-1,3,2-oxazaphosphinan-2-amide 2-oxide
CAS Number	22089-22-1 Y
PubChem CID	65702
ChemSpider	59129 N
UNII	H64JRU6GJ0
KEGG	D07252 Y
ChEMBL	ChEMBL462019 N
Chemical and physical data
Formula	C9H18Cl3N2O2P
Molar mass	323.58 g·mol−1
3D model (JSmol)	Interactive image
SMILES C1CN(P(=O)(OC1)N(CCCl)CCCl)CCCl
InChI InChI=1S/C9H18Cl3N2O2P/c10-2-6-13-5-1-9-16-17(13,15)14(7-3-11)8-4-12/h1-9H2 N Key:UMKFEPPTGMDVMI-UHFFFAOYSA-N N
NY (what is this?)  (verify)

Trofosfamide (INN) is a nitrogen mustard alkylating agent. It is sometimes abbreviated "TRO". It has been used in trials to study its effects on ependymoma, medulloblastoma, sarcoma, soft tissue, supratentorial PNET, and recurrent brain tumors.