Chemistry:N-tert-Butyltryptamine
 | |
 | |
| Clinical data | |
|---|---|
| Other names | N-t-Butyltryptamine; NtBT; NTBT |
| Routes of administration | Oral[1][2] |
| Drug class | Psychoactive drug |
| ATC code |
|
| Pharmacokinetic data | |
| Duration of action | Unknown[1] |
| Identifiers | |
| |
| CAS Number | |
| PubChem CID | |
| ChemSpider | |
| Chemical and physical data | |
| Formula | C14H20N2 |
| Molar mass | 216.328 g·mol−1 |
| 3D model (JSmol) | |
| |
| |
N-tert-Butyltryptamine (NtBT) is a psychoactive drug of the tryptamine family related to psychedelics like dimethyltryptamine (DMT).[1][2][3]
Use and effects
NtBT was briefly described by Alexander Shulgin in his book TiHKAL (Tryptamines I Have Known and Loved).[1] According to Shulgin, NtBT is active at a dose of 5 to 20 mg or of ~20 mg orally.[1][2] He also said that he had heard that NtBT is extremely potent when smoked, but had not received any particulars or confirmed that.[1] Its effects included a lightheaded intoxication described as a totally pleasant buzz, but nothing more profound than that.[1]
Shulgin has said that along with N-sec-butyltryptamine (NsBT), it is one of only two N-mono-substituted tryptamines with known psychoactivity.[1] He also said that N-mono-substituted tryptamines might be GHB-like intoxicants devoid of psychedelic effects.[1] However, N-methyltryptamine (NMT) has been reported to produce psychedelic effects.[1][4][5]
Chemistry
Analogues of NtBT include N-methyltryptamine (NMT), N-ethyltryptamine (NET), N-isopropyltryptamine (NiPT), N-benzyltryptamine (NBnT), 4-HO-DsBT, and 4-HO-McPeT, among others.[1]
See also
References
- ↑ 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 "N-Ethyltryptamine". TiHKAL entry. Erowid.org. http://www.erowid.org/library/books_online/tihkal/tihkal49.shtml. "The tertiary-butyl analogue, NTBT, is the remaining mono-substituted tryptamine that just might have psychotropic potential. In the 5 to 20 milligram area, there is a light-headed intoxication that is a totally pleasant buzz, but nothing more profound than that. Wouldn't it be fascination of it turned out that all of the mono-tryptamines (the NRT's) were GHB-like intoxicants, and totally devoid of psychedelic activity. That would be a true challenge to the SAR crowd. I was told many years ago that NTBT was extremely potent when smoked, but I never received any particulars, and I must leave that as a baseless rumor."
- ↑ 2.0 2.1 2.2 "Basic Pharmacology and Effects". Hallucinogens: A Forensic Drug Handbook. Forensic Drug Handbook Series. Elsevier Science. 2003. pp. 67–137. ISBN 978-0-12-433951-4. https://web.archive.org/web/20250223164514/https://citeseerx.ist.psu.edu/document?repid=rep1&type=pdf&doi=6bb3a7499da8e9852b39cd4db16891147c83f5c6.
- ↑ Hallucinogens: A Forensic Drug Handbook. Academic Press. 2003. pp. 98–99. ISBN 978-0-12-433951-4.
- ↑ Nen (4 December 2011). "Entheogenic effects of NMT from Acacia". Entheogenesis Australis (EGA) Conference, Victoria, Australia, 2–5 December 2011. https://www.dmt-nexus.me/forum/default.aspx?g=posts&m=300323&%23post300323. Retrieved 15 April 2025.
- ↑ Nen (13 July 2013). "NMT: A Spatial Hallucinogen With Therapeutic Applications". Breaking Convention: The Second Multidisciplinary Conference on Psychedelic Consciousness, University of Greenwich, London, 12–14 July 2013. https://www.youtube.com/watch?v=98WXxyb2u4A.
External links
 |  |
