Chemistry:Bephenium hydroxynaphthoate

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Short description: Chemical compound
Bephenium hydroxynaphthoate
Bephenium hydroxynaphthoate.svg
Clinical data
Pregnancy
category
  • Undefined
Routes of
administration
Oral
ATC code
Pharmacokinetic data
Bioavailability<1%
ExcretionRenal (negligible)
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC28H29NO4
Molar mass443.543 g·mol−1
3D model (JSmol)
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Bephenium hydroxynaphthoate (INN, trade names Alcopara, Alcopar, Befenium, Debefenium, Francin, Nemex) is an anthelmintic agent formerly used in the treatment of hookworm infections and ascariasis.[1][2] It is formulated as a salt between the active pharmaceutical ingredient, bephenium, and 3-hydroxy-2-naphthoic acid.[citation needed]

Bephenium is not FDA-approved and is not available in the United States .[3]

References

  1. Sweetman S, ed (2009). Martindale: The complete drug reference (36th ed.). London: Pharmaceutical Press. pp. 143. ISBN 978-0-85369-840-1. 
  2. "Bephenium hydroxynaphthoate in treatment of ascariasis". Br Med J 2 (5194): 268–71. July 1960. doi:10.1136/bmj.2.5194.268. PMID 14406934. 
  3. Pham PA (March 19, 2009). "Bephenium hydroxynaphthoate". Point-of-Care Information Technology ABX Guide. Johns Hopkins University. http://www.hopkinsguides.com/hopkins/view/Johns_Hopkins_ABX_Guide/540057/all/Bephenium_hydroxynaphthoate.  Retrieved on March 25, 2011.