Chemistry:Chlorisondamine

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Short description: Chemical compound
Chlorisondamine
Chlorisondamine.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
Chemical and physical data
FormulaC14H20Cl6N2
Molar mass429.03 g·mol−1
3D model (JSmol)
 ☒N☑Y (what is this?)  (verify)

Chlorisondamine is a nicotinic acetylcholine receptor antagonist that produces both neuronal and ganglionic blockade.

Chlorisondamine has been shown to form noncovalent complexes with various biomolecules including sphingomyelin and other associated glycolipids.[1][2][3]

References

  1. "Interaction of chlorisondamine with the neuronal nicotinic acetylcholine receptor". Journal of Proteome Research 2 (2): 207–12. 2003. doi:10.1021/pr025578h. PMID 12716135. 
  2. "Direct tissue analysis of phospholipids in rat brain using MALDI-TOFMS and MALDI-ion mobility-TOFMS". Journal of the American Society for Mass Spectrometry 16 (2): 133–8. February 2005. doi:10.1016/j.jasms.2004.10.002. PMID 15694763. 
  3. "Lipid/peptide/nucleotide separation with MALDI-ion mobility-TOF MS". Analytical Chemistry 76 (8): 2187–95. April 2004. doi:10.1021/ac035376k. PMID 15080727.