Chemistry:Glutamate-1-semialdehyde

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Glutamate-1-semialdehyde
Glutamate-1-semialdehyde.svg
Names
Preferred IUPAC name
(4S)-4-Amino-5-oxopentanoic acid
Identifiers
3D model (JSmol)
ChemSpider
MeSH glutamate-1-semialdehyde
UNII
Properties
C5H9NO3
Molar mass 131.131 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Glutamate-1-semialdehyde is a molecule formed from by the reduction of tRNA bound glutamate, catalyzed by glutamyl-tRNA reductase. It is isomerized by glutamate-1-semialdehyde 2,1-aminomutase to give aminolevulinic acid in the biosynthesis of porphyrins, including heme and chlorophyll.[1][2]

See also

References

  1. Beale SI (August 1990). "Biosynthesis of the Tetrapyrrole Pigment Precursor, delta-Aminolevulinic Acid, from Glutamate". Plant Physiol. 93 (4): 1273–9. doi:10.1104/pp.93.4.1273. PMID 16667613. 
  2. Willows, R.D. (2004). "Chlorophylls". in Goodman, Robert M.. Encyclopaedia of Plant and Crop Science. Marcel Dekker. pp. 258–262. ISBN 0-8247-4268-0.