Chemistry:Miotine

Miotine

Names
IUPAC name [3-[1-(Dimethylamino)ethyl]phenyl] N-methylcarbamate
Identifiers
CAS Number	4464-16-8 Y
3D model (JSmol)	Interactive image
ChemSpider	41955 N
KEGG	C11763 N
PubChem CID	46093
UNII	9Z3ZT09RRU Y
InChI InChI=1S/C12H18N2O2/c1-9(14(3)4)10-6-5-7-11(8-10)16-12(15)13-2/h5-9H,1-4H3,(H,13,15) N Key: KQOUPMYYRQWZLI-UHFFFAOYSA-N N InChI=1/C12H18N2O2/c1-9(14(3)4)10-6-5-7-11(8-10)16-12(15)13-2/h5-9H,1-4H3,(H,13,15) Key: KQOUPMYYRQWZLI-UHFFFAOYAX
SMILES CC(C1=CC(=CC=C1)OC(=O)NC)N(C)C
Properties
Chemical formula	C12H18N2O2
Molar mass	222.288 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is YN ?)
Infobox references

Tracking categories (test):

• SizeSet

Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.

Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.

Miotine equilibrium

See also

• Neostigmine
• T-1123
• TL-1238
• TMTFA