Chemistry:TL-1238
From HandWiki
Short description: Chemical compound
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| Names | |
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| Preferred IUPAC name
3-[(Dimethylcarbamoyl)oxy]-N,N-diethyl-N-methylanilinium iodide | |
| Other names
Substance 3393
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| Identifiers | |
3D model (JSmol)
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| ChemSpider | |
PubChem CID
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| UNII | |
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| Properties | |
| C14H23IN2O2 | |
| Molar mass | 378.254 g·mol−1 |
| Hazards | |
| Main hazards | Extremely toxic |
| Lethal dose or concentration (LD, LC): | |
LD50 (median dose)
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175 μg/kg (subcutaneous, mice)[1] 89 μg/kg (intravenous, mice)[1] 60 μg/kg (intravenous, mice)[2] |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
TL-1238 (Substance 3393) is an extremely potent carbamate acetylcholinesterase inhibitor. It has been shown to be more potent than neostigmine.[2][3]
See also
References
- ↑ 1.0 1.1 Chemical Warfare Agents, and Related Chemical Problems. Parts I-II. https://ntrl.ntis.gov/NTRL/dashboard/searchResults/titleDetail/PB158508.xhtml.
- ↑ 2.0 2.1 Bülbring, E; Chou, TC (March 1947). "The relative activity of prostigmine homologues and other substances as antagonists to tubocurarine.". British Journal of Pharmacology and Chemotherapy 2 (1): 8–22. doi:10.1111/j.1476-5381.1947.tb00316.x. PMID 19108106.
- ↑ BLASCHKO, H; BULBRING, E; CHOU, TC (March 1949). "Tubocurarine antagonism and inhibition of cholinesterases.". British Journal of Pharmacology and Chemotherapy 4 (1): 29–32. doi:10.1111/j.1476-5381.1949.tb00512.x. PMID 18113150.
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