Chemistry:Normustine
From HandWiki
Short description: Nitrogen mustard used as a chemotherapy agent
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| Other names | Bis(2-chloroethyl)carbamic acid |
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| Formula | C5H9Cl2NO2 |
| Molar mass | 186.03 g·mol−1 |
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Normustine, also known as bis(2-chloroethyl)carbamic acid, is a nitrogen mustard and alkylating antineoplastic agent (i.e., chemotherapy agent).[1][2][3] It is a metabolite of a number of antineoplastic agents that have been developed for the treatment of tumors, including estramustine phosphate, alestramustine, cytestrol acetate, and ICI-85966 (stilbostat), but only the former of which has actually been marketed.[1][2][3]
References
- ↑ 1.0 1.1 Goodman and Gilman's The Pharmacological Basis of Therapeutics, Twelfth Edition. McGraw Hill Professional. 14 January 2011. p. 1709. ISBN 978-0-07-176939-6. https://books.google.com/books?id=e_yAOpyyaowC.
- ↑ 2.0 2.1 Antitumor Drug Resistance. Springer Science & Business Media. 6 December 2012. pp. 199–. ISBN 978-3-642-69490-5. https://books.google.com/books?id=m-TrCAAAQBAJ&pg=PA199.
- ↑ 3.0 3.1 Design of Hybrid Molecules for Drug Development. Elsevier Science. 5 April 2017. pp. 201–. ISBN 978-0-08-101118-8. https://books.google.com/books?id=gfEbDQAAQBAJ&pg=PA201.
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