Chemistry:Spasmolytic A29

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Short description: Antispasmodic drug


Spasmolytic A29
Clinical data
Other namesN,N-Dimethyl-4,4-diphenylbut-3-en-2-amine
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
Chemical and physical data
FormulaC18H21N
Molar mass251.373 g·mol−1
3D model (JSmol)

A29[1][2] is a spasmolytic drug. It not used by itself but is co-administered with ketobemidone in a formulation sold as Ketogan. It is an analog of both amitriptyline and diphenhydramine.

See also

  • BW247
  • DPH-362

References

  1. "Studies on a new spasmolytic compound 1,1-diphenyl-3-dimethylaminobutene-1 (A29), related to methadone, and on the combined use of this compound and a potent analgesic, ketobemidone (A21)". Acta Pharmacologica et Toxicologica 7 (1): 51–64. 1951. doi:10.1111/j.1600-0773.1951.tb02849.x. PMID 14829296. 
  2. "Opioid analgesics as noncompetitive N-methyl-D-aspartate (NMDA) antagonists". Biochemical Pharmacology 56 (5): 553–9. September 1998. doi:10.1016/s0006-2952(98)00088-4. PMID 9783723. 

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