Chemistry:Mephenoxalone

Mephenoxalone
Clinical data
Trade names	Dorsiflex, Moderamin, Control-OM
AHFS/Drugs.com	International Drug Names
ATC code	N05BX01 (WHO) ;
Legal status
Legal status	BR: Class C1 (Other controlled substances) ;
Identifiers
	IUPAC name 5-[(2-methoxyphenoxy)methyl]-1,3-oxazolidin-2-one;
CAS Number	70-07-5 ;
PubChem CID	6257;
ChemSpider	6021 ;
UNII	CZ87T54W8W;
KEGG	D07318 ;
ChEMBL	ChEMBL2104790 ;
Chemical and physical data
Formula	C11H13NO4
Molar mass	223.228 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C2OC(COc1c(OC)cccc1)CN2;
	InChI InChI=1S/C11H13NO4/c1-14-9-4-2-3-5-10(9)15-7-8-6-12-11(13)16-8/h2-5,8H,6-7H2,1H3,(H,12,13) ; Key:ZMNSRFNUONFLSP-UHFFFAOYSA-N ;
	(what is this?) (verify)

Short description: Muscle relaxant

Mephenoxalone (trade names Dorsiflex, Moderamin, Control-OM) is a muscle relaxant^[1] and mild anxiolytic.^[2] It inhibits neuron transmission, relaxing skeletal muscles by inhibiting the reflex arc.^{[citation needed]} As the effect of muscle relaxation, mephenoxalone affects mental condition, and is also a treatment for nervousness and anxiety.

References

↑ "[The utilization in psychotherapy of a tensiolytic agent with muscle relaxant effect, Control OM (mephenoxalone), alone or associated with thymoleptics]". Therapeutische Umschau. Revue Therapeutique 18: 516–20. December 1961. PMID 14468333.
↑ MIMS: Mephenoxalone

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[1] "[The utilization in psychotherapy of a tensiolytic agent with muscle relaxant effect, Control OM (mephenoxalone), alone or associated with thymoleptics]". Therapeutische Umschau. Revue Therapeutique 18: 516–20. December 1961. PMID 14468333.

[2] MIMS: Mephenoxalone

[1]

[2]

v t e Anxiolytics (N05B)
5-HT_1AR agonists	Buspirone Gepirone^† Tandospirone
GABA_AR PAMs	Benzodiazepines: Adinazolam Alprazolam Bromazepam Camazepam Chlordiazepoxide Clobazam Clonazepam Clorazepate Clotiazepam Cloxazolam Diazepam^# Ethyl loflazepate Etizolam Fludiazepam Halazepam Ketazolam Lorazepam^# Medazepam Nordazepam Oxazepam Pinazepam Prazepam; Others: Alpidem^‡ Barbiturates (e.g., phenobarbital) Carbamates (e.g., meprobamate) Chlormezanone^‡ Ethanol (alcohol) Etifoxine Imepitoin; Herbs: Kava Skullcap Valerian
Gabapentinoids (α₂δ VDCC blockers)	Gabapentin Gabapentin enacarbil Phenibut Pregabalin
Antidepressants	SSRIs (e.g., escitalopram) SNRIs (e.g., duloxetine) SARIs (e.g., trazodone) TCAs (e.g., clomipramine^#) TeCAs (e.g., mirtazapine) MAOIs (e.g., phenelzine); Others: Agomelatine Bupropion Tianeptine Vilazodone Vortioxetine
Sympatholytics (Antiadrenergics)	Alpha-1 blockers (e.g., prazosin) Alpha-2 agonists (e.g., clonidine, dexmedetomidine, guanfacine) Beta blockers (e.g., propranolol)
Others	Benzoctamine Cannabidiol Cycloserine Fabomotizole Hydroxyzine Kanna Lavender Lorpiprazole Mebicar Mepiprazole Nicotine Opipramol Oxaflozane^‡ Phenaglycodol Phenibut Picamilon Selank Tiagabine Tofisopam Validolum
^#WHO-EM ^‡Withdrawn from market Clinical trials: ^†Phase III ^§Never to phase III

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