Chemistry:Mazaticol
From HandWiki
Short description: Chemical compound
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| Routes of administration | Oral |
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| Formula | C21H27NO3S2 |
| Molar mass | 405.57 g·mol−1 |
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Mazaticol (Pentona) is an anticholinergic used as an antiparkinsonian agent in Japan.
The compound was known as PG-501 is first mentioned in Japanese studies in the early 1970s, noting "PG-501 was found to have pronounced anti-acetylcholine, anti-tremorine-induced tremor, anti-physostigmine-induced death, anti-haloperidol-induced parkinsonism and anti EEG arousal activities."[1][2]
References
- ↑ "[Pharmacological properties of 6,6,9-trimethyl-9-azabicyclo (3,3,1)non-3 beta-yl-alpha, alpha-di(2-thienyl) glycolate hydrochloride monohydrate (PG-501), a new anti-parkinsonian agent]" (in Japanese). Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica 67 (4): 387–405. July 1971. doi:10.1254/fpj.67.387. PMID 5000167.
- ↑ "パ ー キ ン ソ ン病 に対 す るPG-501の 使 用 経 験/The Beneficial Effect of PG-501 on Parkinsonism". Rinsho Yakuri/Japanese Journal of Clinical Pharmacology and Therapeutics 2 (3): 230–235. 1971. doi:10.3999/jscpt.2.230. https://www.jstage.jst.go.jp/article/jscpt1970/2/3/2_3_230/_article/-char/en. Retrieved December 18, 2023.
External links
- Government registered description of mazaticol (Pentona) (Japanese)[yes|permanent dead link|dead link}}]
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