Biology:SLC7A1

Generic protein structure example

High affinity cationic amino acid transporter 1 is a protein that in humans is encoded by the SLC7A1 gene.

See also

• Solute carrier family

Further reading

• "Molecular cloning and characterization of a novel human gene homologous to the murine ecotropic retroviral receptor". Virology 185 (1): 10–7. November 1991. doi:10.1016/0042-6822(91)90748-Z. PMID 1718082. 
• "Identification of three cationic amino acid transporters in placental trophoblast: cloning, expression, and characterization of hCAT-1". The Journal of Membrane Biology 171 (1): 55–62. September 1999. doi:10.1007/s002329900558. PMID 10485994. 
• "Analysis of the genomic organization of the human cationic amino acid transporters CAT-1, CAT-2 and CAT-4". Amino Acids 21 (2): 211–9. 2002. doi:10.1007/s007260170029. PMID 11665818. 
• "Stable polarized expression of hCAT-1 in an epithelial cell line". The Journal of Membrane Biology 186 (1): 23–30. March 2002. doi:10.1007/s00232-001-0133-y. PMID 11891586. 
• "Lysine uptake by cloned hCAT-2B: comparison with hCAT-1 and with trophoblast surface membranes". The Journal of Membrane Biology 189 (1): 27–33. September 2002. doi:10.1007/s00232-002-1001-0. PMID 12202949. 
• "System y+ localizes to different membrane subdomains in the basolateral plasma membrane of epithelial cells". American Journal of Physiology. Cell Physiology 283 (6): C1784-94. December 2002. doi:10.1152/ajpcell.00061.2002. PMID 12388095. 
• "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proceedings of the National Academy of Sciences of the United States of America 99 (26): 16899–903. December 2002. doi:10.1073/pnas.242603899. PMID 12477932. 
• "The importance of cationic amino acid transporter expression in human skin". The Journal of Investigative Dermatology 120 (6): 1016–22. June 2003. doi:10.1046/j.1523-1747.2003.12139.x. PMID 12787129. 
• "Cell signalling-mediating insulin increase of mRNA expression for cationic amino acid transporters-1 and -2 and membrane hyperpolarization in human umbilical vein endothelial cells". Pflügers Archiv 448 (4): 383–94. July 2004. doi:10.1007/s00424-004-1261-x. PMID 15064952. 
• "Augmented arginine uptake, through modulation of cationic amino acid transporter-1, increases GFR in diabetic rats". Kidney International 65 (4): 1311–9. April 2004. doi:10.1111/j.1523-1755.2004.00508.x. PMID 15086470. 
• "Protein kinase C activation promotes the internalization of the human cationic amino acid transporter hCAT-1. A new regulatory mechanism for hCAT-1 activity". The Journal of Biological Chemistry 279 (52): 54185–92. December 2004. doi:10.1074/jbc.M409556200. PMID 15491978. 
• "Rate of transport of l-arginine is independent of the expression of inducible nitric oxide synthase in HEK 293 cells". Nitric Oxide 12 (1): 21–30. February 2005. doi:10.1016/j.niox.2004.11.001. PMID 15631944. 
• "Identification of a novel polymorphism in the 3'UTR of the L-arginine transporter gene SLC7A1: contribution to hypertension and endothelial dysfunction". Circulation 115 (10): 1269–74. March 2007. doi:10.1161/CIRCULATIONAHA.106.665836. PMID 17325243. 
• "Polyamines upregulate the mRNA expression of cationic amino acid transporter-1 in human retinal pigment epithelial cells". American Journal of Physiology. Cell Physiology 293 (2): C729-37. August 2007. doi:10.1152/ajpcell.00018.2007. PMID 17494634.