Biology:SLC46A1

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A representation of the 3D structure of the protein myoglobin showing turquoise α-helices.
Generic protein structure example

Solute carrier family 46 (folate transporter), member 1 (SLC46A1) also known as proton-coupled folate transporter (PCFT), is a protein which in humans is encoded by the SLC46A1 gene.[1][2][3]

Function

SLC46A1 is responsible for the intestinal uptake of folate.[4]

References

  1. "Entrez Gene: PCFT proton-coupled folate transporter". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=113235. 
  2. "Identification of an intestinal heme transporter". Cell 122 (5): 789–801. September 2005. doi:10.1016/j.cell.2005.06.025. PMID 16143108. 
  3. "Heme carrier protein 1 (HCP1) expression and functional analysis in the retina and retinal pigment epithelium". Exp. Cell Res. 313 (6): 1251–9. April 2007. doi:10.1016/j.yexcr.2007.01.019. PMID 17335806. 
  4. "Functional characterization of human proton-coupled folate transporter/heme carrier protein 1 heterologously expressed in mammalian cells as a folate transporter". J. Pharmacol. Exp. Ther. 322 (2): 469–76. August 2007. doi:10.1124/jpet.107.122606. PMID 17475902. 

Further reading


External links

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