Biology:SLC39A1
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 Generic protein structure example |
Zinc transporter ZIP1 is a protein that in humans is encoded by the SLC39A1 gene.[1] [2][3]
The protein ZIP1 is responsible for the active transport of zinc into prostate cells. In many prostate cancers SLC39A1 is silenced causing prostate cancer cells to be low in zinc.[4]
See also
References
- ↑ "Isolation and characterization of human and mouse ZIRTL, a member of the IRT1 family of transporters, mapping within the epidermal differentiation complex". Genomics 62 (2): 272–80. Feb 2000. doi:10.1006/geno.1999.5993. PMID 10610721.
- ↑ "Functional expression of the human hZIP2 zinc transporter". J Biol Chem 275 (8): 5560–4. Mar 2000. doi:10.1074/jbc.275.8.5560. PMID 10681536.
- ↑ "Entrez Gene: SLC39A1 solute carrier family 39 (zinc transporter), member 1". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=27173.
- ↑ "The clinical relevance of the metabolism of prostate cancer; zinc and tumor suppression: connecting the dots". Mol. Cancer 5: 17. 2006. doi:10.1186/1476-4598-5-17. PMID 16700911.
Further reading
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