Biology:SLC7A5

Generic protein structure example

Solute carrier family 7 member 5 also known as large neutral amino acids transporter small subunit 1 is a protein that in humans is encoded by the SLC7A5 gene.

See also

• Heterodimeric amino acid transporter

Further reading

• "Prognostic significance of L-type amino acid transporter 1 (LAT1) and 4F2 heavy chain (CD98) expression in stage I pulmonary adenocarcinoma.". Lung Cancer 66 (1): 120–6. 2009. doi:10.1016/j.lungcan.2008.12.015. PMID 19171406. 
• "New glycoprotein-associated amino acid transporters.". J. Membr. Biol. 172 (3): 181–92. 1999. doi:10.1007/s002329900595. PMID 10568788. 
• "L-type amino acid transporter 1 as a potential molecular target in human astrocytic tumors.". Int. J. Cancer 119 (3): 484–92. 2006. doi:10.1002/ijc.21866. PMID 16496379. 
• "High expression of L-type amino acid transporter 1 in infiltrating glioma cells.". Brain Tumor Pathol 22 (2): 89–91. 2005. doi:10.1007/s10014-005-0188-z. PMID 18095110. 
• "Production and characterization of highly tumor-specific rat monoclonal antibodies recognizing the extracellular domain of human L-type amino-acid transporter 1.". Cancer Sci. 99 (5): 1000–7. 2008. doi:10.1111/j.1349-7006.2008.00770.x. PMID 18294274. 
• "Functional characterization of tyrosine transport in fibroblast cells from healthy controls.". Neurosci. Lett. 434 (1): 56–60. 2008. doi:10.1016/j.neulet.2008.01.028. PMID 18262359. 
• Endou H, Kanai Y (1999). "[Amino acid transporter molecule as a drug target]". Nippon Yakurigaku Zasshi 114 Suppl 1: 11P-16P. PMID 10629848. 
• "Expression of LAT1 predicts risk of progression of transitional cell carcinoma of the upper urinary tract.". Virchows Arch. 451 (3): 681–90. 2007. doi:10.1007/s00428-007-0457-9. PMID 17622555. 
• "L-type amino acid transporter 1 (LAT1) is frequently expressed in thymic carcinomas but is absent in thymomas.". J Surg Oncol 99 (7): 433–8. 2009. doi:10.1002/jso.21277. PMID 19347882. 
• "Examination of association of genes in the serotonin system to autism.". Neurogenetics 10 (3): 209–16. 2009. doi:10.1007/s10048-009-0171-7. PMID 19184136. 
• "A novel five-antibody immunohistochemical test for subclassification of lung carcinoma.". Mod. Pathol. 22 (8): 1032–43. 2009. doi:10.1038/modpathol.2009.60. PMID 19430419. 
• "Expression of L-type amino acid transporter 1 (LAT1) in neuroendocrine tumors of the lung.". Pathol. Res. Pract. 204 (8): 553–61. 2008. doi:10.1016/j.prp.2008.02.003. PMID 18440724. 
• "Enhanced tumor growth elicited by L-type amino acid transporter 1 in human malignant glioma cells.". Neurosurgery 62 (2): 493-503; discussion 503-4. 2008. doi:10.1227/01.neu.0000316018.51292.19. PMID 18382329. 
• "Genetic polymorphisms in the amino acid transporters LAT1 and LAT2 in relation to the pharmacokinetics and side effects of melphalan.". Pharmacogenet. Genomics 17 (7): 505–17. 2007. doi:10.1097/FPC.0b013e3280ea77cd. PMID 17558306. 
• "Prognostic significance of L-type amino acid transporter 1 expression in resectable stage I-III nonsmall cell lung cancer.". Br. J. Cancer 98 (4): 742–8. 2008. doi:10.1038/sj.bjc.6604235. PMID 18253116. 
• Bröer S (2008). "Amino acid transport across mammalian intestinal and renal epithelia.". Physiol. Rev. 88 (1): 249–86. doi:10.1152/physrev.00018.2006. PMID 18195088. 
• "l-type amino acid transporter 1 and CD98 expression in primary and metastatic sites of human neoplasms.". Cancer Sci. 99 (12): 2380–6. 2008. doi:10.1111/j.1349-7006.2008.00969.x. PMID 19018776. 
• "L-type amino acid transporter 1 expression is a prognostic marker in patients with surgically resected stage I non-small cell lung cancer.". Histopathology 54 (7): 804–13. 2009. doi:10.1111/j.1365-2559.2009.03300.x. PMID 19635099. 
• Shennan DB, Thomson J (2008). "Inhibition of system L (LAT1/CD98hc) reduces the growth of cultured human breast cancer cells.". Oncol. Rep. 20 (4): 885–9. doi:10.3892/or_00000087. PMID 18813831. 
• "L-type amino-acid transporter 1 as a novel biomarker for high-grade malignancy in prostate cancer.". Pathol. Int. 59 (1): 7–18. 2009. doi:10.1111/j.1440-1827.2008.02319.x. PMID 19121087.