Biology:Zinc transporter ZIP6
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Short description: Protein found in humans
 Generic protein structure example |
Zinc transporter ZIP6 is a protein that in humans is encoded by the SLC39A6 gene.[1][2][3]
Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A6 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003).[supplied by OMIM][3]
See also
References
- ↑ "The LZT proteins; the LIV-1 subfamily of zinc transporters". Biochim Biophys Acta 1611 (1–2): 16–30. Mar 2003. doi:10.1016/S0005-2736(03)00048-8. PMID 12659941.
- ↑ "Structure-function analysis of LIV-1, the breast cancer-associated protein that belongs to a new subfamily of zinc transporters". Biochem J 375 (Pt 1): 51–9. Sep 2003. doi:10.1042/BJ20030478. PMID 12839489.
- ↑ 3.0 3.1 "Entrez Gene: SLC39A6 solute carrier family 39 (zinc transporter), member 6". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=25800.
Further reading
- "Effects of oestrogen on the expression of a 4.4 kb mRNA in the ZR-75-1 human breast cancer cell line". Mol. Cell. Endocrinol. 59 (3): 205–12. 1988. doi:10.1016/0303-7207(88)90105-0. PMID 2903103.
- "Genes that co-cluster with estrogen receptor alpha in microarray analysis of breast biopsies". Pharmacogenomics J. 1 (2): 135–41. 2002. doi:10.1038/sj.tpj.6500022. PMID 11911440.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Gene expression patterns in ovarian carcinomas". Mol. Biol. Cell 14 (11): 4376–86. 2004. doi:10.1091/mbc.E03-05-0279. PMID 12960427.
- "Signal peptide prediction based on analysis of experimentally verified cleavage sites". Protein Sci. 13 (10): 2819–24. 2005. doi:10.1110/ps.04682504. PMID 15340161.
- "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. 2004. doi:10.1101/gr.2596504. PMID 15489334.
- "Expression levels of the putative zinc transporter LIV-1 are associated with a better outcome of breast cancer patients". Int. J. Cancer 117 (6): 961–73. 2005. doi:10.1002/ijc.21235. PMID 15986450.
- "LIV-1 suppression inhibits HeLa cell invasion by targeting ERK1/2-Snail/Slug pathway". Biochem. Biophys. Res. Commun. 363 (1): 82–8. 2007. doi:10.1016/j.bbrc.2007.08.127. PMID 17825787.
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