Biology:SLC22A7
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Solute carrier family 22 member 7 is a protein that in humans is encoded by the gene SLC22A7.[1][2][3]
The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.[3]
Interactive pathway map
See also
- SLC22A7+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)
References
- ↑ "Identification of multispecific organic anion transporter 2 expressed predominantly in the liver". FEBS Lett 429 (2): 179–82. Jul 1998. doi:10.1016/S0014-5793(98)00585-7. PMID 9650585.
- ↑ "Assignment of liver-specific organic anion transporter (SLC22A7) to human chromosome 6 bands p21.2→p21.1 using radiation hybrids". Cytogenet Cell Genet 88 (1–2): 76–7. Jun 2000. doi:10.1159/000015489. PMID 10773670.
- ↑ 3.0 3.1 "Entrez Gene: SLC22A7 solute carrier family 22 (organic anion transporter), member 7". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=10864.
Further reading
- "Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP". Mol. Pharmacol. 73 (4): 1151–8. 2008. doi:10.1124/mol.107.043117. PMID 18216183.
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. 2003. doi:10.1073/pnas.242603899. PMID 12477932. Bibcode: 2002PNAS...9916899M.
- "Interaction of human organic anion transporters 2 and 4 with organic anion transport inhibitors". J. Pharmacol. Exp. Ther. 301 (3): 797–802. 2002. doi:10.1124/jpet.301.3.797. PMID 12023506.
- "Human organic anion transporters and human organic cation transporters mediate renal transport of prostaglandins". J. Pharmacol. Exp. Ther. 301 (1): 293–8. 2002. doi:10.1124/jpet.301.1.293. PMID 11907186.
- "Human organic anion transporters mediate the transport of tetracycline". Jpn. J. Pharmacol. 88 (1): 69–76. 2002. doi:10.1254/jjp.88.69. PMID 11855680.
- "Isolation of a family of organic anion transporters from human liver and kidney". Biochem. Biophys. Res. Commun. 283 (2): 417–22. 2001. doi:10.1006/bbrc.2001.4774. PMID 11327718.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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