Biology:Electroneutral sodium bicarbonate exchanger 1
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Short description: Protein-coding gene in the species Homo sapiens
 Generic protein structure example |
Electroneutral sodium bicarbonate exchanger 1 is a protein that in humans is encoded by the SLC4A8 gene.[1][2]
See also
Interactions
SLC4A8 has been shown to interact with Sodium-hydrogen antiporter 3 regulator 1[3][4] and Cystic fibrosis transmembrane conductance regulator.[4]
References
- ↑ "Cloning, characterization, and chromosomal mapping of a human electroneutral Na+-driven Cl−HCO3 exchanger". J Biol Chem 276 (11): 8358–63. May 2001. doi:10.1074/jbc.C000716200. PMID 11133997.
- ↑ "Entrez Gene: SLC4A8 solute carrier family 4, sodium bicarbonate cotransporter, member 8". https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9498.
- ↑ "The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction". Am. J. Physiol., Cell Physiol. 284 (3): C667–73. March 2003. doi:10.1152/ajpcell.00225.2002. PMID 12444018.
- ↑ 4.0 4.1 "The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3− salvage transporter human Na+-HCO3− cotransport isoform 3". J. Biol. Chem. 277 (52): 50503–9. December 2002. doi:10.1074/jbc.M201862200. PMID 12403779.
Further reading
- "Na+:HCO3− cs (NBC): expression and regulation in the kidney". J. Nephrol. 15 (Suppl 5): S32–40. 2002. PMID 12027220.
- "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. 2006. doi:10.1101/gr.4039406. PMID 16344560.
- "Towards a proteome-scale map of the human protein-protein interaction network". Nature 437 (7062): 1173–8. 2005. doi:10.1038/nature04209. PMID 16189514. Bibcode: 2005Natur.437.1173R.
- "Regulation of the human NBC3 Na+/HCO3− cotransporter by carbonic anhydrase II and PKA". Am. J. Physiol., Cell Physiol. 286 (6): C1423–33. 2004. doi:10.1152/ajpcell.00382.2003. PMID 14736710.
- "The COOH termini of NBC3 and the 56-kDa H+-ATPase subunit are PDZ motifs involved in their interaction". Am. J. Physiol., Cell Physiol. 284 (3): C667–73. 2003. doi:10.1152/ajpcell.00225.2002. PMID 12444018.
- "The cystic fibrosis transmembrane conductance regulator interacts with and regulates the activity of the HCO3− salvage transporter human Na+-HCO3− cotransport isoform 3". J. Biol. Chem. 277 (52): 50503–9. 2003. doi:10.1074/jbc.M201862200. PMID 12403779.
- "Immunolocalization of electroneutral Na+-HCO cotransporters in human and rat salivary glands". Am. J. Physiol. Gastrointest. Liver Physiol. 283 (2): G473–80. 2002. doi:10.1152/ajpgi.00421.2001. PMID 12121896.
- "Characterization of Na+/HCO3− cotransporter isoform NBC-3". Am. J. Physiol. 276 (6 Pt 2): F903–13. 1999. doi:10.1152/ajprenal.1999.276.6.F903. PMID 10362779.
- "Cloning, tissue distribution, genomic organization, and functional characterization of NBC3, a new member of the sodium bicarbonate cotransporter family". J. Biol. Chem. 274 (23): 16569–75. 1999. doi:10.1074/jbc.274.23.16569. PMID 10347222.
- "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. 1999. doi:10.1093/dnares/5.5.277. PMID 9872452.
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