Biology:SLC25A4

Generic protein structure example

ADP/ATP translocase 1 is an enzyme that in humans is encoded by the SLC25A4 gene or adenine nucleotide translocator, ANT.

Interactions

SLC25A4 has been shown to interact with Bcl-2-associated X protein.

Further reading

• "Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator". Cell Death and Differentiation 7 (12): 1146–54. Dec 2000. doi:10.1038/sj.cdd.4400778. PMID 11175251. 
• "Mitochondrial control of cell death induced by HIV-1-encoded proteins". Annals of the New York Academy of Sciences 926: 149–64. 2001. doi:10.1111/j.1749-6632.2000.tb05609.x. PMID 11193032. 
• "Partner molecules of accessory protein Vpr of the human immunodeficiency virus type 1". DNA and Cell Biology 23 (4): 193–205. Apr 2004. doi:10.1089/104454904773819789. PMID 15142377. 
• "The role of Vpr in HIV-1 pathogenesis". Current HIV Research 3 (1): 43–51. Jan 2005. doi:10.2174/1570162052772988. PMID 15638722. 
• "The Vpr protein from HIV-1: distinct roles along the viral life cycle". Retrovirology 2: 11. 2006. doi:10.1186/1742-4690-2-11. PMID 15725353. 
• "HIV-1 viral protein R (Vpr) & host cellular responses". The Indian Journal of Medical Research 121 (4): 270–86. Apr 2005. PMID 15817944. 
• "Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanism". Cell Death and Differentiation 12 Suppl 1: 962–70. Aug 2005. doi:10.1038/sj.cdd.4401583. PMID 15832179. 
• "Roles of HIV-1 auxiliary proteins in viral pathogenesis and host-pathogen interactions". Cell Research 15 (11-12): 923–34. 2006. doi:10.1038/sj.cr.7290370. PMID 16354571. 
• "Role of HIV Vpr as a regulator of apoptosis and an effector on bystander cells". Molecules and Cells 21 (1): 7–20. Feb 2006. PMID 16511342. 
• "DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase". Journal of Molecular Biology 206 (2): 261–80. Mar 1989. doi:10.1016/0022-2836(89)90477-4. PMID 2541251. 
• "A human muscle adenine nucleotide translocator gene has four exons, is located on chromosome 4, and is differentially expressed". The Journal of Biological Chemistry 264 (24): 13998–4004. Aug 1989. PMID 2547778. 
• "cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes". Proceedings of the National Academy of Sciences of the United States of America 84 (21): 7580–4. Nov 1987. doi:10.1073/pnas.84.21.7580. PMID 2823266. 
• "Two distinct genes for ADP/ATP translocase are expressed at the mRNA level in adult human liver". Proceedings of the National Academy of Sciences of the United States of America 85 (2): 377–81. Jan 1988. doi:10.1073/pnas.85.2.377. PMID 2829183. 
• "The human skeletal muscle adenine nucleotide translocator gene maps to chromosome 4q35 in the region of the facioscapulohumeral muscular dystrophy locus". Human Genetics 92 (2): 198–203. Sep 1993. doi:10.1007/BF00219692. PMID 8103757. 
• "Deficiency of the adenine nucleotide translocator in muscle of a patient with myopathy and lactic acidosis: a new mitochondrial defect". Pediatric Research 33 (4 Pt 1): 412–7. Apr 1993. doi:10.1203/00006450-199304000-00019. PMID 8479824. 
• "An autosomal locus predisposing to multiple deletions of mtDNA on chromosome 3p". American Journal of Human Genetics 58 (4): 763–9. Apr 1996. PMID 8644740. 
• "Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis". Science 281 (5385): 2027–31. Sep 1998. doi:10.1126/science.281.5385.2027. PMID 9748162. 
• "A third locus predisposing to multiple deletions of mtDNA in autosomal dominant progressive external ophthalmoplegia". American Journal of Human Genetics 65 (1): 256–61. Jul 1999. doi:10.1086/302445. PMID 10364542. 
• "The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore". The Journal of Experimental Medicine 191 (1): 33–46. Jan 2000. doi:10.1084/jem.191.1.33. PMID 10620603. 

External links

• SLC25A4+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)