Chemistry:11β-Hydroxydihydrotestosterone
From HandWiki
| Names | |
|---|---|
| IUPAC name
11β,17β-dihydroxy-5α-androstan-3-one
| |
| Systematic IUPAC name
(5S,8S,9S,10S,11S,13S,14S,17S)-11,17-dihydroxy-10,13-dimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one | |
| Other names
5α-androstan-11β,17β-diol-3-one
| |
| Identifiers | |
3D model (JSmol)
|
|
| ChemSpider | |
PubChem CID
|
|
| |
| |
| Properties | |
| C19H30O3 | |
| Molar mass | 306.446 g·mol−1 |
| Hazards | |
| GHS pictograms | 
|
| GHS Signal word | Danger |
| H351, H360 | |
| P201, P202, P281, P308+313, P405, P501 | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
11β-Hydroxydihydrotestosterone is an endogenous steroid.[1][2][3] Although it may not have significant androgenic activity, it may still be an important precursor to androgenic molecules.[3]
See also
External links
- An entry in the LIPID MAPS database: https://www.lipidmaps.org/databases/lmsd/LMST02020136
References
- ↑ "11β-Hydroxydihydrotestosterone and 11-ketodihydrotestosterone, novel C19 steroids with androgenic activity: a putative role in castration resistant prostate cancer?". Mol Cell Endocrinol 377 (1–2): 135–46. September 2013. doi:10.1016/j.mce.2013.07.006. PMID 23856005.
- ↑ Van Rooyen, D.; Gent, R.; Barnard, L.; Swart, A. C. (2018). "The in vitro metabolism of 11β-hydroxyprogesterone and 11-ketoprogesterone to 11-ketodihydrotestosterone in the backdoor pathway". The Journal of Steroid Biochemistry and Molecular Biology 178: 203–212. doi:10.1016/j.jsbmb.2017.12.014. PMID 29277707.
- ↑ 3.0 3.1 "Alternative androgen pathways". WikiJournal of Medicine 10: X. 2023. doi:10.15347/WJM/2023.003.
 |  |
