Chemistry:4-Methoxyestrone

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4-Methoxyestrone
4-Methoxyestrone.svg
Names
IUPAC name
3-Hydroxy-4-methoxyestra-1,3,5(10)-trien-17-one
Systematic IUPAC name
(3aS,3bR,9bS,11aS)-7-Hydroxy-6-methoxy-11a-methyl-2,3,3a,3b,4,5,9b,10,11,11a-decahydro-1H-cyclopenta[a]phenanthren-1-one
Other names
4-ME1; 4-MeOE1; 4-MeO-E1; 4-Hydroxyestrone 4-methyl ether
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
UNII
Properties
C19H24O3
Molar mass 300.398 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Tracking categories (test):

4-Methoxyestrone (4-ME1) is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estrone that is formed by catechol O-methyltransferase via the intermediate 4-hydroxyestrone.[1][2][3] It has estrogenic activity similarly to estrone and 4-hydroxyestrone.[4]


See also

References

  1. Wishart, David S.; Djombou Feunang, Yannick; Marcu, Ana; Guo, An Chi; Liang, Kevin; Vázquez Fresno, Rosa; Sajed, Tanvir; Johnson, Daniel et al.. "Showing metabocard for 4-Methoxyestrone". https://hmdb.ca/metabolites/http://www.hmdb.ca/metabolites/HMDB60088. 
  2. Hemnes, Anna R. (16 December 2015). Gender, Sex Hormones and Respiratory Disease: A Comprehensive Guide. Humana Press. pp. 32–. ISBN 978-3-319-23998-9. https://books.google.com/books?id=4So3CwAAQBAJ&pg=PA32. 
  3. Lauritzen, Christian; Studd, John W. W. (22 June 2005). Current Management of the Menopause. CRC Press. pp. 378–379. ISBN 978-0-203-48612-2. https://books.google.com/books?id=WD7S7677xUUC&pg=PA378. 
  4. "Comparison of pharmacokinetics of a conjugated equine estrogen preparation (premarin) and a synthetic mixture of estrogens (C.E.S.) in postmenopausal women". Journal of the Society for Gynecologic Investigation 7 (3): 175–83. 2000. doi:10.1016/s1071-5576(00)00049-6. PMID 10865186.