Chemistry:4-Methoxyestradiol
From HandWiki
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| Names | |
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| IUPAC name
4-Methoxyestra-1,3,5(10)-triene-3,17β-diol
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| Systematic IUPAC name
(1S,3aS,3bR,9bS,11aS)-6-Methoxy-11a-methyl-2,3,3a,3b,4,5,9b,10,11,11a-decahydro-1H-cyclopenta[a]phenanthrene-1,7-diol | |
| Other names
4-ME2; 4-MeOE2; 4-MeO-E2; 4-Methoxy-17β-estradiol; Estra-1,3,5(10)-trien-3,4,17β-triol 4-methyl ether
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C19H26O3 | |
| Molar mass | 302.414 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
4-Methoxyestradiol (4-ME2) is an endogenous, naturally occurring methoxylated catechol estrogen and metabolite of estradiol that is formed by catechol O-methyltransferase via the intermediate 4-hydroxyestradiol.[1][2][3] It has estrogenic activity similarly to estrone and 4-hydroxyestrone.[4]
See also
References
- ↑ "Human Metabolome Database: Showing metabocard for 4-Methoxy-17beta-estradiol (HMDB0012782)". http://www.hmdb.ca/metabolites/HMDB12782.
- ↑ Anna R. Hemnes (16 December 2015). Gender, Sex Hormones and Respiratory Disease: A Comprehensive Guide. Humana Press. pp. 32–. ISBN 978-3-319-23998-9. https://books.google.com/books?id=4So3CwAAQBAJ&pg=PA32.
- ↑ Christian Lauritzen; John W. W. Studd (22 June 2005). Current Management of the Menopause. CRC Press. pp. 378–379. ISBN 978-0-203-48612-2. https://books.google.com/books?id=WD7S7677xUUC&pg=PA378.
- ↑ "Comparison of pharmacokinetics of a conjugated equine estrogen preparation (premarin) and a synthetic mixture of estrogens (C.E.S.) in postmenopausal women". J. Soc. Gynecol. Investig. 7 (3): 175–83. 2000. doi:10.1016/s1071-5576(00)00049-6. PMID 10865186.
External links
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