Chemistry:7α-Hydroxyepiandrosterone
From HandWiki
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| Names | |
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| IUPAC name
3β,7α-Dihydroxy-5α-androstan-17-one
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| Systematic IUPAC name
(3aS,3bR,4R,5aR,7S,9aS,9bS,11aS)-4,7-Dihydroxy-9a,11a-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-1-one | |
| Other names
7α-OH-EPIA; 5α-Androstan-3β,7α-diol-17-one
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| Identifiers | |
3D model (JSmol)
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PubChem CID
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| Properties | |
| C19H30O3 | |
| Molar mass | 306.446 g·mol−1 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
Tracking categories (test):
7α-Hydroxyepiandrosterone (7α-OH-EPIA), also known as 3β,7α-dihydroxy-5α-androstan-17-one, is an endogenous, naturally occurring metabolite of epiandrosterone and dehydroepiandrosterone (DHEA) that is formed by the enzyme CYP7B1 in tissues such as the liver and brain.[1][2][3]
See also
References
- ↑ Neurosteroids and Brain Function. Academic Press. 12 December 2001. pp. 90–. ISBN 978-0-08-054423-6. https://books.google.com/books?id=BJumUEbiaPYC&pg=PA90.
- ↑ MORFIN Robert (20 December 2010). Les stéroïdes naturels de A à Z. Lavoisier. pp. 427–. ISBN 978-2-7430-1918-1. https://books.google.com/books?id=SZ31AQAAQBAJ&pg=PA427.
- ↑ "7alpha- and 7beta-hydroxy-epiandrosterone as substrates and inhibitors for the human 11beta-hydroxysteroid dehydrogenase type 1". J. Steroid Biochem. Mol. Biol. 105 (1–5): 159–65. 2007. doi:10.1016/j.jsbmb.2006.11.021. PMID 17624766.
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