Chemistry:8-Bromotheophylline

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Short description: Chemical compound
8-Bromotheophylline
8-Bromotheophylline.svg
Clinical data
Other namesBromotheophylline
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC7H7BrN4O2
Molar mass259.063 g·mol−1
3D model (JSmol)

8-Bromotheophylline is a xanthine diuretic drug. It is the main active ingredient in pamabrom where it is sold as an over-the-counter medication in combination with paracetamol, among other analgesics, to treat dysmenorrhea.[1][2] It is also an adenosine receptor A1 antagonist.[3]

See also

References

  1. "Naproxen, paracetamol and pamabrom versus paracetamol, pyrilamine and pamabrom in primary dysmenorrhea: a randomized, double-blind clinical trial". Medwave 16 (9): e6587. October 2016. doi:10.5867/medwave.2016.09.6587. PMID 27813503. 
  2. "Primary dysmenorrhea among Mexican university students: prevalence, impact and treatment". European Journal of Obstetrics, Gynecology, and Reproductive Biology 152 (1): 73–77. September 2010. doi:10.1016/j.ejogrb.2010.04.015. PMID 20478651. 
  3. "Effect of trifluoromethyl and other substituents on activity of xanthines at adenosine receptors". Journal of Medicinal Chemistry 36 (18): 2639–2644. September 1993. doi:10.1021/jm00070a007. PMID 8410976.