Chemistry:ATL-444
From HandWiki
Short description: Chemical compound
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| Formula | C17H19N5O |
| Molar mass | 309.373 g·mol−1 |
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ATL-444 is a drug which acts as a potent and reasonably selective antagonist for the adenosine receptors A1 and A2A. It has been used to study the role of the adenosine receptor system in the reinforcing action of cocaine,[1] as well as the development of some cancers.[2]
See also
References
- ↑ "Time and sex-dependent effects of an adenosine A2A/A1 receptor antagonist on motivation to self-administer cocaine in rats". Pharmacology, Biochemistry, and Behavior 102 (2): 257–63. August 2012. doi:10.1016/j.pbb.2012.05.001. PMID 22579716.
- ↑ "Adenosine induces intrinsic apoptosis via the PI3K/Akt/mTOR signaling pathway in human pharyngeal squamous carcinoma FaDu cells". Oncology Letters 15 (5): 6489–6496. May 2018. doi:10.3892/ol.2018.8089. PMID 29616118.
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