Chemistry:Puerarin

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Puerarin
Puerarin.svg
Names
IUPAC name
8-(β-D-Glucopyranosyl)-4′,7-dihydroxyisoflavone
Systematic IUPAC name
7-Hydroxy-3-(4-hydroxyphenyl)-8-[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]-4H-1-benzopyran-4-one
Other names
Daidzein-8-C-glucoside
7,4'-Dihydroxy-8-C-glucosylisoflavone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
KEGG
UNII
Properties
C21H20O9
Molar mass 416.382 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Puerarin, one of several known isoflavones, is found in a number of plants and herbs, such as the root of the kudzu plant[1]

Puerarin is the 8-C-glucoside of daidzein.[2]

List of plants that contain the chemical

Notes and references

  1. Dennis K.Y. Yeunga; Susan W.S. Leung; Yan Chun Xua; Paul M. Vanhouttea; Ricky Y.K. Mana (2006). "Puerarin, an isoflavonoid derived from Radix puerariae, potentiates endothelium-independent relaxation via the cyclic AMP pathway in porcine coronary artery". European Journal of Pharmacology 552 (1–3): 105–11. doi:10.1016/j.ejphar.2006.08.078. PMID 17027964. 
  2. "NPI-031G (puerarin) reduces anxiogenic effects of alcohol withdrawal or benzodiazepine inverse or 5-HT2C agonists". Pharmacology Biochemistry and Behavior 75 (3): 619–625. 2003. doi:10.1016/S0091-3057(03)00114-X. PMID 12895679. 
  3. Wang, Lingzhao et al. (2009). "Investigation of supercritical fluid extraction of puerarin from Pueraria Lobata". Journal of Food Process Engineering (John Wiley & Sons) 32 (5): 682–691. doi:10.1111/j.1745-4530.2007.00238.x. 
  4. Chen, Gang et al. (2001). "Determination of puerarin, daidzein and rutin in Pueraria lobata (Wild.) Ohwi by capillary electrophoresis with electrochemical detection". Journal of Chromatography A (Elsevier) 923 (1–2): 255–262. doi:10.1016/S0021-9673(01)00996-7. PMID 11510548. 
  5. Kintzios, Spiridon et al. (2004). "Scale-up production of puerarin from hairy roots of Pueraria phaseoloides in an airlift bioreactor". Biotechnology Letters (Springer) 26 (13): 1057–1059. doi:10.1023/B:BILE.0000032963.41208.e8. ISSN 0141-5492. PMID 15218379. 
  6. Shi, H. P; S. Kintzies (2003). "Genetic transformation of Pueraria phaseoloides with Agrobacterium rhizogenes and puerarin production in hairy roots". Plant Cell Reports (Springer) 21 (11): 1103–1107. doi:10.1007/s00299-003-0633-6. ISSN 0721-7714. PMID 12836005.