Chemistry:CCPA (biochemistry)
From HandWiki
CCPA}}
Names | |
---|---|
IUPAC name
2-Chloro-N6-cyclopentyladenosine
| |
Systematic IUPAC name
(2R,3R,4S,5R)-2-[2-Chloro-6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol | |
Identifiers | |
3D model (JSmol)
|
|
Abbreviations | CCPA |
ChEMBL | |
ChemSpider | |
MeSH | 2-chloro-N(6)cyclopentyladenosine |
PubChem CID
|
|
| |
| |
Properties | |
C15H20ClN5O4 | |
Molar mass | 369.80 g/mol |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
verify (what is ?) | |
Infobox references | |
Tracking categories (test):
2-Chloro-N6-cyclopentyladenosine (CCPA) is a specific receptor agonist for the Adenosine A1 receptor.[1] It is similar to N6-cyclopentyladenosine. Due to CCPA's high affinity for Adenosine A1 receptors, its tritiated derivative [3H]CCPA can be used as a diagnostic tool for detecting the receptors in tissue with low receptor density.[2]
References
- ↑ Karl-Norbert Klotz; Martin J. Lohse; Ulrich Schwabe; Gloria Cristalli; Sauro Vittori; Mario Grifantini (1989). "2-Chloro-N6-[3H]cyclopentyladenosine ([3HCCPA) — a high affinity agonist radioligand for A1 adenosine receptors". Naunyn-Schmiedeberg's Archives of Pharmacology 340 (6): 679–683. doi:10.1007/BF00717744. PMID 2615857.
- ↑ Klotz, Karl-Norbert; Lohse, Martin J.; Schwabe, Ulrich; Cristalli, Gloria; Vittori, Sauro; Grifantini, Mario (1989-12-01). "2-Chloro-N6-[3Hcyclopentyladenosine ([3HCCPA) —a high affinity agonist radioligand for A1 adenosine receptors"] (in en). Naunyn-Schmiedeberg's Archives of Pharmacology 340 (6): 679–683. doi:10.1007/BF00717744. ISSN 1432-1912. PMID 2615857. https://doi.org/10.1007/BF00717744.
Original source: https://en.wikipedia.org/wiki/CCPA (biochemistry).
Read more |